MoviePick
Poster for Common Side Effects (2025)

TV series · Returning Series

Common Side Effects (2025)

  • Feb 2, 2025
  • 2 seasons · 11 episodes
  • TV-MA

8.5/10

TMDB user score
367 votes on TMDB

Play trailer Where to watch

About This Series

Common Side Effects is an animation and drama series created by Joseph Bennett and Steve Hely. Its leading cast includes Dave King, Emily Pendergast and Mike Judge. It premiered on February 2, 2025 on Adult Swim. TMDB lists 2 seasons and 11 episodes so far and is listed as a returning series.

Synopsis

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

Synopsis from TMDB.

Before You Pick

Time to finish
About 4 hours, based on 11 episodes at 23 minutes each
Ending
Ongoing: more episodes are expected
Age rating (US)
TV-MA
Language
English
Audience signal
8.5/10 from 367 TMDB votes

Official Trailer

Official Trailer [Adult Swim Europe] · plays from YouTube

Where to Watch Common Side Effects

Stream with a subscription

  • HBO Max Amazon Channel
  • YouTube TV
  • Adult Swim
  • HBO Max

Free with ads

  • Adult Swim

Buy

  • Amazon Video
  • Apple TV Store
  • Google Play Movies
  • Fandango At Home

See prices and links on TMDB

Availability from JustWatch via TMDB. Services and prices change often, so confirm with the provider. MoviePick does not host or stream video.

Cast

  • Dave King Marshall Cuso (voice) 11 episodes
  • Emily Pendergast Frances Applewhite (voice) 10 episodes
  • Mike Judge Rick Kruger (voice) 10 episodes
  • Martha Kelly Agent Harrington (voice) 10 episodes
  • Joseph Lee Anderson Agent Copano (voice) 10 episodes
  • Sue Rose Hildy (voice) 8 episodes
  • Shannon Woodward Amelia (voice) 8 episodes
  • Ben Feldman Frat Guy (voice) 8 episodes
  • Sydney Tamiia Poitier Cecily (voice) 7 episodes
  • Shalita Grant Susan (voice) 6 episodes
  • Danny Huston Jonas Backstein (voice) 6 episodes
  • Steve Hely Rusty (voice) 6 episodes
  • Christine Ko Kiki (voice) 5 episodes
  • Alan Resnick Zane (voice) 3 episodes
  • Lin Shaye Sonia (voice) 3 episodes
  • Bob Stephenson Connor (voice) 3 episodes
  • Timothy Simons DEA Dispatcher (voice) 3 episodes
  • Jon Foor Hoang (voice) 3 episodes

Seasons

Next episode: season 2, episode 1, airs Jan 24, 2027.

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